'Annihilation' volgt een groep van vier vrouwen: een bioloog, een antropoloog, een psycholoog en een surveillant. De groep besluit op een gevaarlijke expeditie te gaan naar een locatie waar de natuurwetten niet gelden.
| Writing | Jeff VanderMeer | Novel |
| Directing | Alex Garland | Director |
| Production | Andrew Macdonald | Producer |
| Editing | Barney Pilling | Editor |
| Art | Mark Digby | Production Design |
| Crew | Clare St. John | Post Production Supervisor |
| Production | Dana Goldberg | Executive Producer |
| Production | Jo Burn | Executive Producer |
| Art | Gareth Cousins | Art Direction |
| Production | Francine Maisler | Casting |
| Costume & Make-Up | Sammy Sheldon | Costume Design |
| Directing | Matthew Penry-Davey | First Assistant Director |
| Art | Michelle Day | Set Decoration |
| Art | Simon Elsley | Art Direction |
| Production | Don Granger | Executive Producer |
| Production | David Ellison | Executive Producer |
| Art | Elaine Kusmishko | Art Direction |
| Production | Sara Desmond | Unit Production Manager |
| Production | Allon Reich | Producer |
| Writing | Alex Garland | Screenplay |
| Sound | Geoff Barrow | Original Music Composer |
| Sound | Ben Salisbury | Original Music Composer |
| Sound | Robert Malone | Sound Effects Editor |
| Art | Lauren Doss | Art Direction |
| Sound | Danny Freemantle | Sound Effects Editor |
| Crew | Tom Balogh | Visual Effects Editor |
| Visual Effects | Austin Aplin | Visual Effects Coordinator |
| Crew | Tina Richardson | Visual Effects Editor |
| Sound | Glenn Freemantle | Sound Designer |
| Sound | Ian Tapp | Sound Re-Recording Mixer |
| Costume & Make-Up | Charlotte Rogers | Makeup Artist |
| Costume & Make-Up | Samantha Denyer | Makeup Artist |
| Sound | Mitch Low | Production Sound Mixer |
| Art | Denis Schnegg | Supervising Art Director |
| Sound | Niv Adiri | Sound Designer |
| Sound | Ben Barker | Sound Designer |
| Lighting | Chris Georgas | Gaffer |
| Crew | Tristan Versluis | Makeup Effects |
| Visual Effects | Roma O'Connor | Visual Effects Producer |
| Visual Effects | Paul Edwards | Visual Effects Producer |
| Visual Effects | Agnes Toomus | Visual Effects Coordinator |
| Crew | Jessica Atkinson | Visual Effects Editor |
| Visual Effects | Bhumika Mayer | Visual Effects Producer |
| Camera | Sam Phillips | Key Grip |
| Visual Effects | Carlos Ciudad | Visual Effects Producer |
| Visual Effects | Noga Alon Stein | Visual Effects Producer |
| Lighting | Andy Lowe | Gaffer |
| Crew | Sebastian Lochmann | Makeup Effects |
| Crew | Tristan Versluis | Animatronics Supervisor |
| Costume & Make-Up | Sian Grigg | Makeup Designer |
| Art | Muffin Green | Property Master |
| Visual Effects | Emanuele Farnesi | 3D Artist |
| Camera | Rob Hardy | Director of Photography |
| Crew | Dhuha Isa | Visual Effects Editor |
| Art | Lauren Briggs-Miller | Assistant Art Director |
| Crew | Artemis Oikonomopoulou | CG Supervisor |
| Crew | Luca Zappala | CG Supervisor |
| Visual Effects | Paul O'Hara | Visual Effects Coordinator |
| Visual Effects | Alyssa Harrison | Visual Effects Coordinator |
| Crew | Alastair Grimshaw | Visual Effects Editor |
| Costume & Make-Up | Sian Grigg | Hair Designer |
| Visual Effects | Sara Bennett | Visual Effects Supervisor |
| Art | Kira Kemble | Assistant Art Director |
| Visual Effects | Katia Muscariello | Visual Effects Coordinator |
| Camera | Peter Mountain | Still Photographer |
| Visual Effects | Erin Langford | Visual Effects Coordinator |
| Visual Effects | Amir Manavi | Visual Effects Technical Director |
| Camera | Vince McGahon | Steadicam Operator |
| Crew | Sean Schur | Sequence Supervisor |
| Visual Effects | Jeremy Stewart | Animation Supervisor |
| Crew | Nicolas Hernandez | CG Supervisor |
| Visual Effects | Andrew Whitehurst | Visual Effects Supervisor |
| Visual Effects | Simon Hughes | Visual Effects Supervisor |
| Lighting | John Antill | Rigging Gaffer |
| Crew | Russell Oxley | Scenic Artist |
| Visual Effects | Michael Tuohy | Visual Effects Coordinator |
| Camera | Rick Woollard | Additional Camera |
| Crew | Lucia Foster Found | Aerial Coordinator |
| Crew | Sarah Clark | Unit Publicist |
| Editing | Emanuele Giraldo | First Assistant Editor |
| Crew | Tom Ralphs | Armorer |
| Art | Matt Curtis | Title Designer |
| Sound | Glenn Freemantle | Supervising Sound Editor |
| Editing | Gemma Lyons | Digital Intermediate |
| Sound | Emilie O'Connor | Dialogue Editor |
| Crew | Will Samuelson | Pilot |
| Crew | Jonjo Stickland | Marine Coordinator |
| Sound | Gillian Dodders | ADR Supervisor |
| Sound | Lilly Blazewicz | Foley Editor |
| Directing | Victoria Gegenbauer | Script Supervisor |
| Sound | Peter Burgis | Foley |
| Sound | Niv Adiri | Sound Re-Recording Mixer |
| Editing | Otto Rodd | Digital Intermediate |
| Sound | Zoe Freed | Foley |
| Editing | Andrew Scattergood | Digital Intermediate |
| Visual Effects | Hayley J Williams | Special Effects Supervisor |
| Crew | Bobbi Jene Smith | Choreographer |
| Editing | Isabel Zippert | Digital Intermediate |
| Costume & Make-Up | Poli Kyriacou | Assistant Costume Designer |
| Directing | San Davey | Script Supervisor |
| Editing | Tim Drewett | Digital Intermediate |
| Sound | Stephane Malenfant | Boom Operator |
| Production | Martin Ware | Casting Associate |
| Costume & Make-Up | Nicole Young | Costume Supervisor |
| Editing | Ben-Roy Turner | Digital Intermediate |
| Crew | Alana Mayo | Thanks |
| Crew | Daniel Rogers | Health and Safety |
| Production | Scott Rudin | Producer |
| Production | Nina Gold | Casting |
| Production | Joanne Smith | Associate Producer |
| Production | Eli Bush | Producer |
| Directing | Charlie Reed | Second Assistant Director |
| Art | Chloe Taylor | Art Department Assistant |
| Art | Sam Moulsdale | Graphic Designer |
| Art | Jed Evans | Props |
| Art | Ben Johnson | Assistant Property Master |
| Art | Ryan Bradbury | Props |
| Art | Sean Leishman | Props |
| Art | Elo Soode | Concept Artist |
| Costume & Make-Up | Belinda Parish | Makeup Artist |
| Art | Dan Crandon | Construction Manager |
| Art | Gareth Bailey | Props |
| Art | Michael Pybus | Draughtsman |
| Art | Natalie Papageorgiadis | Props |
| Costume & Make-Up | Amie Aspden | Prosthetics Painter |
| Art | Martin Kane | Dressing Prop |
| Costume & Make-Up | Paul Spateri | Prosthetic Makeup Artist |
| Art | Chris Caldow | Concept Artist |
| Art | Stuart Silver | Props |
| Lighting | Pawel Polak | Electrician |
| Art | Steve 'Moose' Smith | Set Dresser |
| Lighting | Daniel Addis | Electrician |
| Lighting | Neil Ashton | Electrician |
| Camera | Cenay Said | Second Assistant Camera |
| Lighting | Andy D. Stewart | Electrician |
| Camera | Jennie Paddon | First Assistant "A" Camera |
| Visual Effects | Gwilym Morris | Animation Supervisor |
| Lighting | Gary Owen | Electrician |
| Art | Lisa McDiarmid | Standby Art Director |
| Lighting | Daniel Chaytor | Electrician |
| Lighting | Christian Hayes | Electrician |
| Visual Effects | Tom Rolfe | 2D Supervisor |
| Art | Dan Riches | Set Dresser |
| Art | Martin Asbury | Storyboard Artist |
| Camera | Matt McNally | Epk Producer |
| Lighting | Daniel Stones | Electrician |
| Camera | Sarah Rollason | First Assistant "B" Camera |
| Lighting | Seth Crosby | Electrician |
| Lighting | Paul Allen | Lighting Technician |
| Art | Mal Zawadzki | Standby Painter |
| Lighting | Kai Blamey | Electrician |
| Camera | George Anthony Fox | Second Assistant Camera |
| Art | Gena Vazquez | Props |
| Art | Elo Soode | Conceptual Design |
| Crew | Jo McLaren | Stunt Coordinator |
| Crew | Josh Wood | Carpenter |
| Crew | Casey Michaels | Stunt Double |
| Crew | Joanne Batten | Stunt Double |
| Crew | Chelsea Mather | Stunt Double |
| Crew | Belinda McGinley | Stunt Double |
| Crew | Karen Teoh | Stunt Double |
| Crew | Mens-Sana Tamakloe | Stunt Double |
| Crew | Maxine Whittaker | Stunts |
| Crew | Pablo Verdejo | Stunts |
| Crew | Leo Woodruff | Stunts |
| Crew | Martin Wilde | Stunts |
| Crew | Martin Pemberton | Stunts |
| Crew | Anthony Skrimshire | Stunts |
| Crew | Darren Malkin | Stunts |
| Crew | Tim Marshall-Rowe | Stunts |
| Crew | Niki Faulkner | Stunts |
| Crew | Andy Godbold | Stunts |
