Nadat de tweeling Milo en Maggie, die van elkaar vervreemd zijn geraakt, op dezelfde dag allebei toevallig aan de dood ontsnappen, besluiten ze samen te komen en hun levens onder de loep te nemen. Ze vragen zich allebei af hoe hun levens zo verkeerd hebben kunnen lopen. Maggie zal haar huwelijk met de brave Lance herbekijken, terwijl haar homoseksuele broer Milo zijn oude vlam Rich opzoekt. De tweeling beseft gaandeweg dat hun onderlinge relatie de sleutel tot een gelukkig leven is.
Nee, helaas is The Skeleton Twins nog niet beschikbaar op Netflix in Nederland.
| Directing | Craig Johnson | Director |
| Writing | Craig Johnson | Writer |
| Sound | Nathan Larson | Original Music Composer |
| Production | Jacob Pechenik | Producer |
| Production | Jennifer Lee | Producer |
| Camera | Reed Morano | Director of Photography |
| Production | Stephanie Langhoff | Producer |
| Writing | Mark Heyman | Writer |
| Production | Avy Kaufman | Casting |
| Art | Ola Maslik | Production Design |
| Art | Lauren DeTitta | Set Decoration |
| Production | Jared Ian Goldman | Executive Producer |
| Costume & Make-Up | Valerie Velez | Hair Department Head |
| Costume & Make-Up | Leo Won | Makeup Department Head |
| Sound | Daniel Heffernan | Sound Editor |
| Editing | Jennifer Lee | Editor |
| Costume & Make-Up | Mikaela Wohl | Costume Design |
| Camera | Reed Morano | Camera Operator |
| Directing | Joseph Ciccarella | First Assistant Director |
| Directing | Anne Marie Dentici | Second Assistant Director |
| Sound | Anton Gold | Sound Mixer |
| Sound | Matt Schoenfeld | Sound Designer |
| Production | Mark Duplass | Executive Producer |
| Production | Jay Duplass | Executive Producer |
| Sound | Ian Stynes | Supervising Sound Editor |
| Sound | Shaun Brennan | Foley Artist |
| Sound | Ian Stynes | Sound Designer |
| Costume & Make-Up | Tamika Jackson | Costume Supervisor |
| Sound | Ian Stynes | Sound Re-Recording Mixer |
| Camera | Clay Enos | Still Photographer |
| Production | Roxie Rodriguez | Associate Producer |
