Charlie Fineman en Alan Johnson zijn oud-studiegenoten die het contact met elkaar verloren hebben. Ze lopen elkaar toevallig tegen het lijf in Manhattan en de vriendschap is snel weer opgepakt.
Nee, helaas is Reign Over Me nog niet beschikbaar op Netflix in Nederland.
| Camera | Russ T. Alsobrook | Director of Photography |
| Costume & Make-Up | Deborah L. Scott | Costume Design |
| Editing | Steve Edwards | Editor |
| Production | Jack Giarraputo | Executive Producer |
| Directing | Mike Binder | Director |
| Production | Lynwood Spinks | Executive Producer |
| Editing | Jeremy Roush | Editor |
| Writing | Mike Binder | Screenplay |
| Crew | Jennifer Lamb | Stunts |
| Costume & Make-Up | Ann Pala | Makeup Department Head |
| Sound | Cameron Steenhagen | Dialogue Editor |
| Sound | Elmo Weber | Sound Re-Recording Mixer |
| Art | Jon Danniells | Set Decoration |
| Sound | David Bach | Supervising Sound Editor |
| Sound | Elmo Weber | Supervising Sound Editor |
| Art | Greg Berry | Art Direction |
| Sound | Marc Glassman | Sound Effects Editor |
| Costume & Make-Up | Gary Archer | Prosthetics |
| Art | Christian Wintter | Production Design |
| Production | Sharon Bialy | Casting |
| Sound | Rolfe Kent | Original Music Composer |
| Sound | Dave Jordan | Music Supervisor |
| Production | Jack Binder | Producer |
| Production | Michael Rotenberg | Producer |
| Directing | Nancy Karlin | Script Supervisor |
| Art | David Swayze | Art Direction |
| Crew | Joanne Lamstein | Stunts |
| Crew | John Cenatiempo | Stunt Driver |
| Crew | Roy Farfel | Stunt Driver |
| Crew | Janet Paparazzo | Stunts |
| Camera | Scott Koche | Camera Production Assistant |
| Crew | George B. Colucci Jr. | Stunts |
| Visual Effects | Vincent Cirelli | Visual Effects Supervisor |
| Camera | Steven A. Adelson | Camera Operator |
