Vier onbekende mensen stappen op een avond in San Francisco nietsvermoedend in de bus. De buschauffeur wordt echter op zeer prettige wijze afgeleid en zij verongelukken allen. Tegelijkertijd wordt tijdens het ongeluk in een van de betrokken auto's Thomas geboren. En juist deze onwillige sterveling is voorbestemd om de onvervulde dromen van de vier ongelukkige zielen te doen uitkomen.
Nee, helaas is Heart and Souls nog niet beschikbaar op Netflix in Nederland.
| Production | Nancy Roberts | Producer |
| Writing | Brent Maddock | Screenplay |
| Sound | Marc Shaiman | Original Music Composer |
| Directing | Ron Underwood | Director |
| Editing | O. Nicholas Brown | Editor |
| Camera | Michael W. Watkins | Director of Photography |
| Production | Sean Daniel | Producer |
| Visual Effects | Tom Martinek | I/O Supervisor |
| Writing | S.S. Wilson | Screenstory |
| Costume & Make-Up | Ken Chase | Key Makeup Artist |
| Directing | Shawn Hanley | Other |
| Directing | Pamela S. Kuri | Second Second Assistant Director |
| Writing | Brent Maddock | Screenstory |
| Art | Danny Hinzo | Painter |
| Art | Anne H. Ahrens | Set Decoration |
| Art | Brad Curry | Other |
| Art | Dean B. Katz | Set Dresser |
| Writing | Erik Hansen | Screenplay |
| Costume & Make-Up | Karen Bradley | Makeup Artist |
| Costume & Make-Up | James R. Scribner | Makeup Artist |
| Art | Geoffrey Lake | Other |
| Production | Pam Dixon | Casting |
| Costume & Make-Up | Dione Taylor | Key Hair Stylist |
| Directing | Yudi Bennett | First Assistant Director |
| Art | John Alvin | Other |
| Art | Horst Grandt | Property Master |
| Writing | Erik Hansen | Screenstory |
| Writing | S.S. Wilson | Screenplay |
| Art | Chris H. Kelly | Construction Foreman |
| Production | Cari-Esta Albert | Executive Producer |
| Production | Gregory Hansen | Co-Producer |
| Production | Dirk Petersmann | Unit Production Manager |
| Art | Gary Gagliardo | Construction Foreman |
| Art | James Holden | Set Dresser |
| Art | John Moore | Other |
| Production | James Jacks | Executive Producer |
| Art | John Muto | Production Design |
| Directing | Daniel Silverberg | Second Assistant Director |
| Art | Douglas E. Maxwell | Leadman |
| Crew | Leopold Mouneau, Jr. | Other |
| Crew | David Castro, Jr. | Other |
| Writing | Gregory Hansen | Screenplay |
| Production | Erik Hansen | Co-Producer |
| Art | Dan Webster | Art Direction |
| Costume & Make-Up | Jean-Pierre Dorléac | Costume Design |
| Costume & Make-Up | JoAnn Stafford-Chaney | Hairstylist |
| Art | Amy Feldman | Other |
| Writing | Gregory Hansen | Screenstory |
| Production | Dixie J. Capp | Associate Producer |
| Art | Mike Helbig | Set Dresser |
| Directing | Polly Ann Mattson | Second Second Assistant Director |
| Directing | Mic Rodgers | Second Unit Director |
| Art | Robert L. King | Other |
| Production | Dirk Petersmann | Line Producer |
| Art | Lori Harrison | Set Dresser |
| Art | John M. Holliday | Construction Foreman |
| Art | Bill Jackson | Art Department Coordinator |
| Art | John Hammer Maxwell | Set Dresser |
| Art | John Berger | Set Designer |
| Crew | John Bullard | Propmaker |
| Art | Ross Harpold | Set Dresser |
| Art | Gary Heider | Other |
| Art | Hugo Herrera | Greensman |
| Crew | Allan Johnson | Other |
| Directing | Shannon Wilson | Second Assistant Director |
| Art | Kristin Argue | Other |
| Art | Steven Lane Ewing | Other |
| Crew | Adam Shankman | Choreographer |
| Crew | John C. Meier | Stunts |
| Crew | Mic Rodgers | Stunt Coordinator |
| Crew | Michael Runyard | Stunts |
| Crew | Sonja Davis | Stunts |
