Revolverheld Hogan redt een nonnetje, zuster Sara, uit handen van een stel dronken bandieten. Vervolgens raken zij samen betrokken bij de Mexicaanse vrijheidsstrijd tegen de Fransen.
Nee, helaas is Two Mules for Sister Sara nog niet beschikbaar op Netflix in Nederland.
| Editing | Robert F. Shugrue | Editor |
| Production | Martin Rackin | Producer |
| Writing | Albert Maltz | Screenplay |
| Production | Carroll Case | Producer |
| Sound | Ennio Morricone | Original Music Composer |
| Camera | Gabriel Figueroa | Director of Photography |
| Directing | Don Siegel | Director |
| Crew | Leon Charles | Dialogue Coach |
| Sound | Waldon O. Watson | Sound |
| Sound | Ronald Pierce | Sound |
| Sound | Stanley Wilson | Music Supervisor |
| Costume & Make-Up | Evelina Casas | Hairstylist |
| Crew | Buddy Van Horn | Stunt Coordinator |
| Directing | Joseph C. Cavalier | Second Unit Director |
| Costume & Make-Up | Helen Colvig | Costume Design |
| Costume & Make-Up | Carlos Chávez | Costume Design |
| Costume & Make-Up | Margarita Ortega | Makeup Artist |
| Sound | Jesús González Gancy | Sound |
| Directing | Joseph C. Cavalier | Assistant Director |
| Costume & Make-Up | Frank Westmore | Makeup Artist |
| Directing | René Cardona | Second Unit Director |
| Crew | Frank Brendel | Special Effects |
| Production | William Davidson | Unit Production Manager |
| Crew | León Ortega | Special Effects |
| Directing | Manuel Muñoz 'Torito' | Assistant Director |
| Production | Alfonso Sánchez Tello | Unit Production Manager |
| Editing | Juan José Marino | Editor |
| Art | José Rodríguez Granada | Art Direction |
| Art | Pablo Galván | Set Decoration |
| Writing | Budd Boetticher | Story |
| Camera | Gabriel Torres | Second Unit Director of Photography |
