De twee vooruitstrevende wetenschappers Elsa Kast en Clive Nicoli experimenteren met dierlijk DNA en het lukt hen deze te verenigen. Het levert een mutant op die behulpzaam zou kunnen zijn bij het genezen van ziekten, maar hun project zal binnenkort worden stopgezet. Ze realiseren zich dat ze niet veel tijd meer hebben en beginnen op eigen houtje, zonder dat iemand er verder van weet, een experiment met dierlijk én menselijk DNA. Het resultaat is verbluffend, maar tegelijk ook zeer riskant...
Nee, helaas is Splice nog niet beschikbaar op Netflix in Nederland.
| Production | Steven Hoban | Producer |
| Production | Guillermo del Toro | Producer |
| Sound | Steve Copley | Foley Recordist |
| Costume & Make-Up | Lydia Pensa | Assistant Hairstylist |
| Editing | Peter Armstrong | Digital Intermediate Producer |
| Costume & Make-Up | Julia Valente | Assistant Makeup Artist |
| Crew | Jane Conway | Animal Wrangler |
| Sound | Michel Monier | Dolby Consultant |
| Art | Marc Kuitenbrouwer | Construction Coordinator |
| Editing | Chris Wallace | Digital Intermediate Colorist |
| Sound | Brandon Prodger | ADR Recordist |
| Directing | Vincenzo Natali | Director |
| Art | Todd Cherniawsky | Production Design |
| Costume & Make-Up | Marie Nardella | Makeup Department Head |
| Art | Joshu de Cartier | Art Direction |
| Production | Jason Knight | Casting |
| Writing | Antoinette Terry Bryant | Screenplay |
| Production | John Buchan | Casting |
| Writing | Vincenzo Natali | Screenplay |
| Production | Constance Demontoy | Casting |
| Costume & Make-Up | Alex Kavanagh | Costume Design |
| Writing | Doug Taylor | Screenplay |
| Art | Sam Hudecki | Assistant Art Director |
| Crew | Daniel White | Special Effects Coordinator |
| Art | William Cheng | Set Designer |
| Sound | Garrett Kerr | Sound Effects Editor |
| Visual Effects | Arnauld Boulard | Visual Effects Producer |
| Visual Effects | Ian Hunter | Visual Effects Supervisor |
| Crew | Paul Rapovski | Stunt Coordinator |
| Directing | Lisa Burling | Script Supervisor |
| Sound | John Sievert | Foley |
| Visual Effects | Fabrice Lagayette | Visual Effects Supervisor |
| Crew | Rossana DeCampo | Scenic Artist |
| Art | Jason Lunn | Leadman |
| Lighting | Chris Howard | Gaffer |
| Crew | Chris Howard | Thanks |
| Sound | Brad Sherman | Sound Re-Recording Mixer |
| Visual Effects | Alain Lalanne | Visual Effects Producer |
| Camera | Angelo Colavecchia | Camera Operator |
| Production | Joseph Boccia | Production Manager |
| Visual Effects | Jacques Bled | Visual Effects Producer |
| Camera | Steve Wilkie | Still Photographer |
| Sound | David McCallum | Supervising Sound Editor |
| Visual Effects | François-Xavier Aubague | Visual Effects Producer |
| Crew | Michael Griffith | Visual Effects Editor |
| Crew | Sue Len Quon | Visual Effects Editor |
| Visual Effects | David Sanger | Visual Effects Producer |
| Editing | Christopher M. Meagher | Digital Intermediate |
| Sound | Shie Rozow | Music Editor |
| Sound | Roderick Deogrades | Sound Effects Editor |
| Crew | Plato Fountidakis | Stunt Coordinator |
| Crew | Dana Howes | Transportation Coordinator |
| Production | Marty Dejczak | Location Manager |
| Costume & Make-Up | Leslie Kavanagh | Costume Supervisor |
| Costume & Make-Up | David R. Beecroft | Hairstylist |
| Sound | Laurent Kossayan | Supervising Sound Editor |
| Sound | Steve Pederson | Sound Re-Recording Mixer |
| Visual Effects | Jean-François Bourrel | Visual Effects Producer |
| Editing | Aidan Stanford | Color Timer |
| Sound | Mark Shnuriwsky | Sound Effects Editor |
| Sound | David Rose | Sound Designer |
| Sound | Stefan Fraticelli | Foley |
| Visual Effects | Bob Munroe | Visual Effects Supervisor |
| Visual Effects | Dale Gagne | Visual Effects Producer |
| Visual Effects | Pierre Buffin | Visual Effects Supervisor |
| Camera | Dino Laurenza | Camera Operator |
| Visual Effects | Christina Butterfield | VFX Artist |
| Sound | Janice Ierulli | Dialogue Editor |
| Camera | Tetsuo Nagata | Director of Photography |
| Writing | Antoinette Terry Bryant | Story |
| Sound | Jill Purdy | Dialogue Editor |
| Sound | Cyrille Aufort | Original Music Composer |
| Sound | Jean-Alexandre Villemer | Sound Recordist |
| Art | James R. Murray | Property Master |
| Editing | Michele Conroy | Editor |
| Writing | Vincenzo Natali | Story |
| Sound | Lou Thomas | Dialogue Editor |
| Crew | Cynthia Amsden | Unit Publicist |
| Production | Franck Chorot | Producer |
| Art | Mario Moreira | Assistant Property Master |
| Camera | Jeff DaSilva | Second Assistant Camera |
| Directing | Bob Munroe | Second Unit Director |
| Lighting | Desiree Lidon | Electrician |
| Camera | David Herrington | Second Unit Director of Photography |
| Crew | Hubert Boorder | Stunt Double |
| Camera | John Colavecchia | First Assistant "B" Camera |
| Crew | Christopher Cordell | Stunt Double |
| Camera | Mark Manchester | Key Grip |
| Camera | Amanda Wojtaszek | Camera Loader |
| Directing | Sarah Campbell | Second Assistant Director |
| Camera | Mark Cyre | First Assistant "A" Camera |
| Directing | Andrew Shea | First Assistant Director |
| Production | John Papsidera | Casting |
| Art | Warner Strauss | Location Scout |
